<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1713 1713-30410 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, M184V, L210W, T215Y V75M, K219R K101E, Y181C, G190A A98G, V108I, F227L K43N, E44D, V90VI, V111I, V118I, K122E, D123N, I135T, I178M, V189I, T200A, E203K, Q207E, H208Y, R211K, H221Y, K223E, L228H, V245M I159L
>1713-30410| codons 38-247
CTELENDGKISKIGPENPYNTPVFAIKKKNSDKWRKLMDFRELNKRTQDFWEIQLGIPHP
GGLEKKKSVTILDIGDAYFSIPLDENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
ALFQSSMTKILEPFRKQNPDMVICQYVDDLYIASDLEIGQHRAKIKELREYLWKWGFYTP
DRKYQEEPPLHWMGYELHPDKWTVQPIMLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54A, V82T, I84V, L90M L33F, Q58E, G73S, L89V L10V, I13V, K20T, E34Q, E35D, M36I, N37ND, K55R, R57K, I62V, L63P, I66F, A71V, I72V, Q92K  
>1713-30410| codons 4-99
TLWQRPVVTVKIGGQLTEALLDTGADDTVFQDIDLPGRWKPKIIGGIGGFARVKEYDQVP
IEFCGHKVVSTVLVGPTPTNVIGRNVMTKIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006