Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1713 | 1713-30410 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, V75M, M184V, L210W, T215Y | K219R | K101E, Y181C, G190A | A98G, V108I, F227L | K43N, E44D, V90VI, V111I, V118I, K122E, D123N, I135T, I178M, V189I, T200A, E203K, Q207E, H208Y, R211K, H221Y, K223E, L228H, V245M | I159L |
| >1713-30410| codons 38-247 CTELENDGKISKIGPENPYNTPVFAIKKKNSDKWRKLMDFRELNKRTQDFWEIQLGIPHP GGLEKKKSVTILDIGDAYFSIPLDENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP ALFQSSMTKILEPFRKQNPDMVICQYVDDLYIASDLEIGQHRAKIKELREYLWKWGFYTP DRKYQEEPPLHWMGYELHPDKWTVQPIMLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54A, V82T, I84V, L90M | L33F, Q58E, G73S, L89V | L10V, I13V, K20T, E34Q, E35D, M36I, N37ND, K55R, R57K, I62V, L63P, I66F, A71V, I72V, Q92K |
| >1713-30410| codons 4-99 TLWQRPVVTVKIGGQLTEALLDTGADDTVFQDIDLPGRWKPKIIGGIGGFARVKEYDQVP IEFCGHKVVSTVLVGPTPTNVIGRNVMTKIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |