Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1711 | 1711-30408 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54M, V82S | L24I, L33F, G73GC | L10I, I13V, I15V, K20R, E35D, M36I, N37E, K43I, L63P, A71V |
| >1711-30408| codons 4-99 TLWQRPIVTVKVGGQLREALIDTGADDTVFEDIELPGRWIPKMIGGIGGFMKVRQYDQIP IEICGHKVICTVLVGPTPSNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y115F, Q151M, M184V | A62V, K70KQ, V75I, F77L, F116Y | Y188L | S68G, K122E, R172K, Q174R, D177E, I178M, V189I, G196E, R211K, F214L |
| >1711-30408| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFVIKKKDGTQWRKLIDLRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAFYSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSP AIFQSSMTKILEPFKKRNPEMVIYQYVDDLLIGSDLEIEQHRTKIEELRQHLLKWGLTTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |