Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1710 | 1710-30403 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82A | L10F, L24I, L33F, F53FL | M36L, I62V, L63P, H69R |
| >1710-30403| codons 4-99 TLWQRPFVTIKIGGQLKEALIDTGADDTVFEELNLPGRWKPKIIGGIGGLVKVRQYDQVP IEICGRKAIGTVLVGPTPANIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, T69D, M184MV, L210LW, T215Y | S162A, H208HY, R211K |
| >1710-30403| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQASMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIGQHRTKIEELRQYLWKWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |