Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1426 | 1426-30401 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, I84V, L90M | L10F, G73S | I13V, I15V, L19P, K20I, M36I, L63P, A71V, I72R |
| >1426-30401| codons 4-99 TLWQRPFVTVKVGGQPIEALLDTGADDTVLEEINLPGRWKPKIIGGIGGFVKVRQYDQIP IEICGHKVRSTVLVGPTPVNVIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74I, L210W, T215Y | K219N | K101E, Y181C, G190A | A98G | E44D, V118I, K122E, D123E, S162C, D177E, G196E, I202V, E203K, H208Y, R211K, K223Q, P243S, V245K |
| >1426-30401| codons 38-247 CTELEKDGKISKIGPENPYNTPVFAIKKKNSTKWRKIVDFRELNKRTQDFWEVQLGIPHP GGLEKKKSVTVLDVGDAYFSIPLDEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILEPFRKQNPEIVICQYMDDLYVASDLEIEQHRTKVKELRQYLWKWGFYTP DNKHQQEPPFLWMGYELHPDKWTVQSIKLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |