Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1413 | 1413-30821 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, K65KR, L74LV, M184MIV, L210LW, T215Y | K70KN, F116FY | K101P, K103N, G190GA | S68G, V90I, K166KR, I178LM, T200A, H208HY, R211K |
| >1413-30821| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKRKDGTNWRKVVDFRELNKRTQDFWEIQLGIPHP AGLPKNKSVTVLDVGDAYYSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTRILEPFRKQNPDMVIYQYVDDLYVASDLEIGQHRAKIEELRQYLWKWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54IV, I84V, L90M | L10FI, V11I, L33I, G73GS, N88ND | I13V, L19V, E35D, M36I, I62IV, L63P, A71AV |
| >1413-30821| codons 4-99 TLWQRPIITVKIGGQVKEALLDTGADDTVIEDINLPGRWKPKMIGGIGGFVKVRQYDQVP IEICGHKVISTVLVGPTPVNVIGRDLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |