Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1407 | 1407-30507 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69DE, K70R, L74V, L210W, T215F | K219Q | K103N, Y181C, G190A | V60I, V118VI, D123E, I135V, K166R, D177E, G196K, I202V, Q207E, R211K, D218E, L228H, V245R |
| >1407-30507| codons 38-247 CTELEKEGKISKIGPENPYNTPIFAIKKKNSERWRKVVDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYFSIPLDKEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP AIFQSSMTRILEPFRKQNPEIVICQYMDDLYVASDLEIKQHRTKVEELREHLWKWGFFTP EQKHQKEPPFHWMGYELHPDKWTVQPIRLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, L76V, V82A, I84IV, L90M | L23I, L33F | L10I, I13V, G16GA, L63P, H69Y, A71V, I72V, V77I, I93L |
| >1407-30507| codons 4-99 TLWQRPIVTVKIAGQLKEAILDTGADDTVFEEMNLPGRWKPKLIGGIGGFVKVRQYDQIP IEICGYKVVGTVVIGPTPANVIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |