<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1779 1779-30605 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, I84V, L90M L10F, V11I, Q58E, G73S T12K, I13V, L19LP, K20I, E35D, M36I, K55R, I62V, L63P, A71T, I72T, T91S  
>1779-30605| codons 4-99
TLWQRPFIKVKIGGQPIEALLDTGADDTVLEDINLPGRWKPKIIGGIGGFVRVREYDQVP
IEICGHKTTSTVLVGPTPVNVIGRNLMSQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, M184V, L210W, T215Y   K103S, V106A, G190A F227L K43Q, E44D, L109I, V118I, K122E, V179I, G196E, T200AE, E203K, Q207E, H208Y, R211K, H221Y, V245Q  
>1779-30605| codons 38-247
CTELEQDGKISKIGPENPYNTPVFAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKSKSATVIDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPDIIIYQYVDDLYVASDLEIEQHREKIKELREYLWKWGFYTP
DKKYQKEPPLLWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006