<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1400 1400-30626 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, V75M, M184V, L210W, T215Y K219Q   A98G K43M, E44D, V60I, V118I, K122E, D123N, I135L, I142V, Q197P, H208Y, R211K, D218E, L228H, V245E  
>1400-30626| codons 38-247
CTELEMDGKISKIGPENPYNTPIFAIKKKNSDKWRKLMDFRELNKRTQDFWEVQLGIPHP
GGLKKKKSVTVLDVGDAYFSIPLDENFRKYTAFTIPSLNNETPGVRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIGPHRTKIEELRQYLWKWGFYTP
EQKHQKEPPFHWMGYELHPDKWTVQPIELP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, I84V, L90M L33F, Q58E K20MR, I62V, L63P, I64M, C67F, A71V, I72T, V77I, T91S, Q92R, I93L  
>1400-30626| codons 4-99
TLWQRPLVTIKIGGQLREALLDTGADDTVFEEMNLPGRWKPKIIGGIGGFVKVREYDQVP
MEIFGHKVTGTVLIGPTPVNVIGRNLMSRLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006