Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1913 | 1913-30515 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V, T215F | K219Q | K103KNRS | T69N, A98S, K122E, I135T, I142V, Q174K, N175Y, G196DE, Q207E, R211K, V245T |
| >1913-30515| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHP SGLKKSKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKKYPDIVIYQYVDDLYVGSDLEIEQHRTKIEELREHLLKWGFFTP DQKHQKEPPFLWMGYELHPDKWTVQPITLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N, I54LV, V82A, L90M | L10F, L33F, N88D | I15V, K20V, E35N, M36I, R41K, I62V, L63P, K70N, A71V, I72V |
| >1913-30515| codons 4-99 TLWQRPFVTIKVGGQLVEALLDTGADNTVFENINLPGKWKPKMIGGIGGFVKVRQYDQVP IEICGHNVVGTVLVGPTPANIIGRDLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |