Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1611 | 1611-30626 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74V, M184V, L210W, T215Y | Y181C, G190GA | V108VI | T39A, K43E, K101Q, K122KE, G196E, Q197K, E203D, H208Y, R211K, V245Q |
| >1611-30626| codons 38-247 CAELEEEGKISKIGPENPYNTPVFAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHP AGLQKKKSVTILDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVICQYVDDLYVASDLEIEKHRTKIDELRQYLWKWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I50V, I54V, L76V, L90M | L10F, G73S, L89LV | I15IV, K20I, E34Q, E35D, M36I, N37D, I62V, L63P, H69QR, I93M | A71FI |
| >1611-30626| codons 4-99 TLWQRPFVTIKVGGQLIEALLDTGADDTVLQDIDLPGRWKPKIIGGVGGFVKVRQYDQVP IEICGRKIISTVVVGPTPVNIIGRNVMTQMGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |