<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-2136 2136-30821 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, M184V, L210W, T215Y K219N K101PQ, Y181C, G190A V108VI, V179VF T39TA, E40F, K43E, K103KR, V118I, K122E, Q174R, T200A, L205F, H208Y, R211K, V245I  
>2136-30821| codons 38-247
CAFLEEEGKISKIGPENPYNTPVFAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHP
AGLQKRKSVTILDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKRNPDIFICQYVDDLYVASDLEIGQHRAKIEEFRQYLWKWGFYTP
DNKHQKEPPFLWMGYELHPDKWTVQPIILP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, I84V, L90M L10F, L33F, N83D K20R, E35D, M36L, R41K, K45V, I62V, L63P, I64V K55Q
>2136-30821| codons 4-99
TLWQRPFVTIKIGGQLREALLDTGADDTVFEDLNLPGKWKPVLIGGIGGFVQVRQYDQVP
VEICGHKAIGTVLVGPTPVDVIGRNLMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006