Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2132 | 2132-30820 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, I84V, L90M | L10I, I13V, K14R, K20I, E35D, M36I, I62V, L63P, I64IV, A71V |
| >2132-30820| codons 4-99 TLWQRPIVTVRIGGQLIEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFVKVRQYDQVP VEICGHKVIGTVLVGPTPANVIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L74LI, M184V, T215F | K219Q | K103NS, G190A | V60I, T69N, K122KE, G196E, T200A, Q207E |
| >2132-30820| codons 38-247 CTELEKEGKISKIGPENPYNTPIFAIKKKNSNRWRKIVDFRELNKRTQDFWEVQLGIPHP AGLKKSKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYVDDLYVASDLEIEQHRAKIEELREHLLRWGFFTP DQKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |