<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1615 1615-30723 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, L74V, L210W, T215Y K219E K101E, Y181C V108I E44D, V118I, K122E, I142V, D192N, E203A, H208Y, R211K, D218E, L228H, V245K  
>1615-30723| codons 38-247
CTELEKDGKISKIGPENPYNTPVFAIKKKNSTRWRKVVDFRELNKRTQDFWEVQLGIPHP
AGLEKKKSVTILDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPDIVICQYMDDLYVGSNLEIGQHRTKIAELRQYLWKWGFYTP
EEKHQKEPPFHWMGYELHPDKWTVQPIKLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V32I, M46MI, I47V, I54L, I84V, L90M   L10I, L19I, K20R, E35D, M36I, N37E, K55KR, D60E, I62V, L63P, A71T, Q92K, I93L  
>1615-30723| codons 4-99
TLWQRPIVTIKIGGQIREALLDTGADDTILEDIELPGRWKPKIVGGIGGFLRVRQYEQVP
IEICGHKTIGTVLVGPTPVNVIGRNLMTKLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006