Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2188 | 2188-30702 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T69D, M184V, L210W, T215Y | D67G, K219R | K103KT | T39A, K43KE, E44A, V60I, K122E, D123N, I132V, I135T, S162C, I167IV, D177E, I178L, V179I, H208HY, R211RK, D218E |
| >2188-30702| codons 38-247 CAELEEAGKISKIGPENPYNTPIFAIKKKGSDKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKTKSVTVLDVGDAYFSVPLDENFRKYTAFTVPSTNNETPGIRYQYNVLPQGWKGSP AIFQCSMTKVLEPFRKQNPELIIYQYVDDLYVGSDLEIGQHRTKIEELRQYLWKWGFYTP ERKHQKEPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I84V, L90M | L10FI, V11VI | T12TP, I13V, I15V, L19IV, K20I, M36I, I62V, L63P, T74S, L89IM, Q92K |
| >2188-30702| codons 4-99 TLWQRPIIPVKVGGQVIEALLDTGADDTVLEEINLPGRWKPKIIGGIGGFIKVRQYDQVP IEICGHKAIGSVLVGPTPVNVIGRNMMTKIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |