Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2064 | 2064-30626 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, K20R, E35D, M36I, N37E |
| >2064-30626| codons 4-99 TLWQRPLVTIKVGGQLREALLDTGADDTVLEDIELPGRWKPKMIGGIGGFIKVRQYDQIL IEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, V75T, M184V, T215Y | K219N | K101P, G190A | S68G, R83K, D123E, K166R, D177E |
| >2064-30626| codons 38-246 CTELEKEGKISKIGPENPYNTPVFAIKKKDGTKWRKVTDFRELNKKTQDFWEVQLGIPHP AGLPKKKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTRILEPFRKQNPEIVIYQYVDDLYVASDLEIGQHRTKIEELRQHLLRWGFYTP DNKHQKEPPFLWMGYELHPDKWTVQPIVL |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |