Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2065 | 2065-30626 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, L210W, T215Y | A98G | E44D, V118I, K122KE, Q174R, T200A, E203D, H208Y, R211K, K223Q |
| >2065-30626| codons 38-247 CTELEKDGKISKIGPENPYNTPVFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHP GGLKKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKRNPDIVIYQYVDDLYVGSDLEIGQHRAKIDELRQYLWKWGFYTP DKKHQQEPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A, L90M | L33LF, F53L, Q58E, G73T | L10I, I15V, G16A, K20R, E35D, M36I, N37E, K55R, R57RK, I62V, L63P, A71I, I72IT, I93L |
| >2065-30626| codons 4-99 TLWQRPIVTIKVAGQLREALLDTGADDTVFEDIELPGRWKPKLIGGIGGLVRVKEYDQVP IEICGHKITTTVLVGPTPANIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |