<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1599 1599-30624 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, K70R, L74V, M184V, T215F D67G, K219E Y181C V108VI E44ED, V60I, S68G, L109LI, D123E, I135T, S162SN, Q174R, Q207E, R211K, D218E, L228LH  
>1599-30624| codons 38-247
CTELEKDGKISKIGPENPYNTPIFAIKKKGGTRWRKVVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTIIDVGDAYFSVPLDKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQNSMTKILEPFRKRNPDIVICQYVDDLYVGSDLEIGQHRTKIEELREHLLKWGFFTP
EEKHQKEPPFHWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A, I84V F53L, Q58QE L10I, I13V, G16A, K20R, E35D, M36I, N37D, Q61K, L63P, A71V, I72E  
>1599-30624| codons 4-99
TLWQRPIVTVKIAGQLREALLDTGADDTVLEDIDLPGRWKPKMIGGIGGLVKVREYDKIP
IEICGHKVEGTVLVGPTPANVIGRNLLTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006