Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2021 | 2021-30714 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74V, M184MV, T215Y | F77L, K219KN | L100I | K122A, D123E, Q174R, D177E, I178M, T200A, Q207E, R211K, L228LH | F116I |
| >2021-30714| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKVVDLRELNKRTQDFWEVQLGIPHP AGIKKKKSVTVLDVGDAYISVPLDAEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKRNPEMVIYQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFYTP DNKHQKEPPFHWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | L10I, E35D, N37D, K45R, I62IV, L63P, K70R, A71V, V77I, I93L |
| >2021-30714| codons 4-99 TLWQRPIVTIKIGGQLKEALLDTGADDTVLEDMDLPGRWKPRMIGGIGGFIKVRQYDQVP IEICGHRVIGTVLIGPTPVNIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |