Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2022 | 2022-30709 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L210W, T215Y | L100I, K103N | K43E, E44D, W88C, V118I, K122E, I135IT, T200E, E203K, R211K |
| >2022-30709| codons 38-247 CTELEEDGKISKIGPENPYNTPVFAIKKKNSDKWRKLVDFRELNKRTQDFCEVQLGIPHP AGIKKNKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHREKIKELRQHLWKWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, I47V, I54L, V82A, L90M | L33F, K43T, F53L | L10V, G16A, L63P, A71L, I93L |
| >2022-30709| codons 4-99 TLWQRPVVTIKIAGQLKEALLDTGADDTIFEEMNLPGRWTPKIVGGIGGLLKVRQYDQIP IEICGHKLIGTVLVGPTPANIIGRNLMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |