Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2024 | 2024-30709 | U.S. | 2003 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | V60VI, K122E, D123S, I135T, K173L, Q174K, D177E, V179I, T200A, Q207A, R211S, V245Q |
| >2024-30709| codons 38-247 CTEMEKEGKISKIGPENPYNTPIFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRLKNPEIIIYQYVDDLYVGSDLEIGQHRAKIEELRAHLLSWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V | L33F, N83D | L10V, I13V, K14R, E35D, M36IL, N37ND, R41K, R57K, H69Q, L89M |
| >2024-30709| codons 4-99 TLWQRPVVTVRIGGQLKEALLDTGADDTVFEDLDLPGKWKPKLIGGIGGFVKVKQYDQIL IEICGQKAIGTVLVGPTPVDIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |