<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-2017 2017-30701 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, K70R, L74V, M184V, L210W, T215F K219W K101P   T39A, K43E, K104N, V118I, K122E, D177G, I178M, V179VI, T200A, H208Y, R211K, D218E, L228H, Q242QH  
>2017-30701| codons 38-247
CAELEEEGKISKIGPENPYNTPVFAIKKKNSDRWRKVVDFRELNKRTQDFWEVQLGIPHP
AGLPKKNSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPGMIIYQYVDDLYVGSDLEIGQHRAKIEELRQYLWKWGFFTP
EWKHQKEPPFHWMGYELHPDKWTVHPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82F G48E, F53L L10I, E35D, M36V, N37H, R41N, L63C, I64V, V77I, I93L  
>2017-30701| codons 4-99
TLWQRPIVTIKIGGQLKEALLDTGADDTVLEDVHLPGNWKPKLIEGIGGLVKVRQYDQIC
VEICGHKAIGTVLIGPTPFNIIGRNLLTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006