Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2015 | 2015-30701 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | L10F, V32A, L33F, K43T, N88D | I13V, I15V, K20T, E35D, M36I, N37S, K45R, R57K, L63P, I64V, V77VI, L89LM |
| >2015-30701| codons 4-99 TLWQRPFVTVKVGGQLTEALLDTGADNTAFEDISLPGRWTPRMIGGIGGFIKVKQYDQIP VEICGHKAIGTVLIGPTPVNIIGRDMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, K70R, T215F | D67H, K219Q | K101EV, G190A | K43E, V60VI, S68SN, T69N, K122E, I135LV, E138EQ, K166R, H208HY, R211K |
| >2015-30701| codons 38-247 CTELEEEGKISKIGPENPYNTPIFAIKKKHNNRWRKLVDFRELNKRTQDFWEVQLGIPHP AGLVKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSVNNQTPGIRYQYNVLPQGWKGSP AIFQSSMTRILEPFRKQNPDIVIYQYMDDLYVASDLEIGQHRTKIEELRQYLLKWGFFTP DQKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |