Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1820 | 1820-30822 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, K70R, L74V, M184V | K219Q | Y181C, G190GA | T39A, E40D, V60I, K122E, D123N, I178M, T200A, E203K, Q207E, V245K |
| >1820-30822| codons 38-247 CADLEKEGKISKIGPENPYNTPIFAIKKKNSDRWRKVVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSVPLDENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDMVICQYVDDLYVASDLEIGQHRAKIKELREHLLRWGFTTP DQKHQKEPPFLWMGYELHPDKWTVQPIKLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54A, V82A | L10F, L24I | I13M, K20I, M36I, R41K, Q61N, L63P, I64V, H69Y |
| >1820-30822| codons 4-99 TLWQRPFVTMKIGGQLIEALIDTGADDTVLEEINLPGKWKPKIIGGIGGFAKVRQYDNIP VEICGYKAIGTVLVGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |