Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2155 | 2155-30721 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, T69D, K70R, L74I, M184V, T215F | K219Q | K103N | A98G | V118I, K122E, I135T, I142V, K166R, F214L, L228H |
| >2155-30721| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKNSDRWRKIVDFRELNKRTQDFWEVQLGIPHP GGLKKNKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSP AIFQSSMTRILEPFRKQNPDIVIYQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGLFTP DQKHQKEPPFHWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, I84V | L10F, V11I, L33F, T74P | I13V, I15V, K20T, E35D, M36I, R41K, K55R, I62V, L63P, L89T |
| >2155-30721| codons 4-99 TLWQRPFITVKVGGQLTEALLDTGADDTVFEDINLPGKWKPKMIGGIGGFVRVRQYDQVP IEICGHKAIGPVLVGPTPVNVIGRNTLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |