<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-2150 2150-30818 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, K70R, L74V, M184V, L210W, T215FY T69G, K219E Y181V V108I T39A, E40D, V60I, K66X, D67X, K102E, V118VI, K122E, I135T, T139TA, S162CY, V179I, T200TA, D218E, H221HY, L228H, Q242H  
>2150-30818| codons 38-247
CADLEKEGKISKIGPENPYNTPIFAIKKXQSGRWRKVVDFRELNKRTQDFWEVQLGIPHP
AGLKEKKSVTILDVGDAYFSIPLDEDFRKYTAFTIPSTNNEAPGIRYQYNVLPQGWKGSP
AIFQYSMTKILEPFRKQNPDIIIVQYVDDLYVGSDLEIGQHRAKIEELRQHLWRWGFYTP
EEKYQKEPPFHWMGYELHPDKWTVHPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54LV, L76V, V82A L33F L10I, I13V, G16E, M36IV, K43KQ, K55R, D60E, Q61D, L63T, C67Y, I72T, T74TS, L89M P39P_EK
>2150-30818| codons 4-99
TLWQRPIVTVKIEGQLKEALLDTGADDTVFEEVNLPGRWQPKIIGGIGGFVRVRQYEDIT
IEIYGHKATGSVVVGPTPANIIGRNMLTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006