<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1572 1572-30508 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I47V, I54M, I84V, L90M L33I L10I, I13V, E35D, M36L, N37D, K55R, R57K, I62V, L63P, I66F, A71V  
>1572-30508| codons 4-99
TLWQRPIVTVKIGGQLKEALLDTGADDTVIEDLDLPGRWKPKLVGGIGGFMRVKQYDQVP
IEFCGHKVIGTVLVGPTPVNVIGRNLMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74I, V75T, L210W, T215Y K219N L100I, K101E, G190A A98G, F227L T39TA, K43Q, E44D, W88C, V118I, K122E, S134SN, E138A, G196GE, E203K, H208Y, R211K, K223E, L228H R83RS
>1572-30508| codons 38-247
CAELEQDGKISKIGPENPYNTPVFAIKKKNSTKWRKITDFRELNKSTQDFCEVQLGIPHP
GGIEKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPNINNATPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVASDLEIEQHRTKIKELRQYLWKWGFYTP
DNKHQEEPPLHWMGYELHPDKWTVQPIVLP

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006