<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1561 1561-30610 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, Q151M, T215F A62V, V75I, F77L, F116Y, K219E Y181I V108I I50IV, T58N, T69N, V90VI, L100V, V106VL, V111I, V118I, K122E, I135T, I202T, R211K, F214C, H221Y, L228H  
>1561-30610| codons 38-247
CTEMEKEGKISKVGPENPYNNPVFVIKKKNSNRWRKLIDLRELNKRTQDFWEIQLGIPHP
AGVKKKKSLTILDIGDAYYSIPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKGSP
AIFQSSMTKILEPFRKQNPDIVIIQYMDDLYVGSDLEIGQHRTKTEELRQHLLKWGCFTP
DEKYQKEPPFHWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A, L90M V11I, G73S L10I, T12S, I13M, I15V, L19M, K20I, M36I, K55R, R57K, I62V, L63P, C67F, A71V, I85V  
>1561-30610| codons 4-99
TLWQRPIISMKVGGQMIEALLDTGADDTVLEEINLPGRWKPKLIGGIGGFVRVKQYDQVP
IEIFGHKVISTVLVGPTPANIVGRNLMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006