Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1233 | 1233-30409 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, M184V, L210W, T215F | G190A | V60I, K101Q, V118I, D121Y, K122E, I135T, S162A, D177E, V179I, R211K, D237E, V245Q |
| >1233-30409| codons 38-247 CTELEKEGKISKIGPENPYNTPIFAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLQKKKSVTVLDVGDAYFSIPLYEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQASMTKILEPFRKQNPEIIIYQYVDDLYVASDLEIGQHRTKIEELRQHLWKWGFFTP DKKHQKEPPFLWMGYELHPEKWTVQPIQLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, I84V, L90M | L10I, T12P, I13IV, I15V, K20T, E35D, N37S, R41K, L63P, A71T |
| >1233-30409| codons 4-99 TLWQRPIVPVKVGGQLTEALLDTGADDTVLEDMSLPGKWKPKIIGGIGGFVKVRQYDQIP IEICGHKTIGTVLVGPTPVNVIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |