<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-2108 2108-30619 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T69D, K70R, Q151M, M184V, T215F K219Q Y181C, G190A K101H, V108I K49Q, A98S, D123E, Q174R, D177E, I178L, V189I, G196E, F214L, D218E  
>2108-30619| codons 38-247
CTEMEKEGKISQIGPENPYNTPVFAIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIPHP
SGLHKKKSVTILDVGDAYFSVPLDKEFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSP
AIFQSSMTKILEPFRKRNPELVICQYVDDLYIASDLEIEQHRTKIEELRQHLLRWGLFTP
EQKHQKEPPFLWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, L76V, V82A, I84V   L10I, I15V, K20R, M36I, N37D, K43S, Q61QK, I62V, L63C, H69R, A71V, I72T, T74AS, I93L  
>2108-30619| codons 4-99
TLWQRPIVTIKVGGQLREALLDTGADDTVLEEIDLPGRWSPKIIGGIGGFVKVRQYDKVC
IEICGRKVTGSVVVGPTPANVIGRNLLTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006