Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1530 | 1530-30807 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82T, L90M | G73S | L10I, E35D, M36I, N37E, I62V, L63P, C67F, A71I, I72K |
| >1530-30807| codons 4-99 TLWQRPIVTIKIGGQLKEALLDTGADDTVLEDIELPGRWKPKMIGGIGGFVKVRQYDQVP IEIFGHKIKSTVLVGPTPTNIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, T69D | D67G | Y181C | V60I, R83K, V118I, G196E, E203D, E204K, Q207E, F214L |
| >1530-30807| codons 38-247 CTEMEKEGKISKIGPENPYNTPIFAIKRKGSDKWRKLVDFRELNKKTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAYFSIPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVICQYMDDLYVGSDLEIEQHRTKIDKLREHLLRWGLTTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |