Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1504 | 1504-30626 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, I47V, I54L, I84V, L90M | L10F, V11I, Q58E, G73S, L89V | I15V, G16A, K20V, F53Y, L63P, T74K, V77I, I85V |
| >1504-30626| codons 4-99 TLWQRPFITIKVAGQLVEALLDTGADDTILEEMNLPGRWKPKIVGGIGGYLKVREYDQIP IEICGHKAISKVLIGPTPVNVVGRNVMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L74I, M184V, L210W, T215Y | V75A | A98G | T39A, K43Q, E44D, V118I, K122E, S162SDGN, E203K, Q207DE, H208Y, R211K, K223Q, L228LF, V245E |
| >1504-30626| codons 38-247 CAELEQDGKISKIGPENPYNTPVFAIKKKNSDKWRKIADFRELNKRTQDFWEVQLGIPHP GGLKKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQNSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIGQHRTKIKELREYLWKWGFYTP DKKHQQEPPFFWMGYELHPDKWTVQPIELP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |