Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1762 | 1762-30417 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T69S_SS, V75M, M184MV, L210W, T215Y | K103S, G190A | V108I | T39A, D86E, W88C, L109I, D123E, I142V, R172K, V179I, Q197K, T200A, Q207E, H221Y |
| >1762-30417| codons 38-247 CAELEKEGKISKIGPENPYNTPVFAIKKKDSSKWRKLMDFRELNKRTQEFCEVQLGIPHP AGLKKSKSVTIIDVGDAYFSVPLDKEFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSP AIFQSSMTKILEPFKKQNPDIIIYQYVDDLYVASDLEIGKHRAKIEELREHLWRWGFYTP DKKYQKEPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82C, I84V, L90M | V11VI, L33F, T74P | L10I, I13V, R41K, I62V, L63P, A71T, I93L | L89R |
| >1762-30417| codons 4-99 TLWQRPIITVKIGGQLKEALLDTGADDTVFEEMNLPGKWKPKLIGGIGGFVKVRQYDQVP IEICGHKTIGPVLVGPTPCNVIGRNRMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |