Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2233 | 2233-30805 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, G48V, V82A, I84V | L10I, G16E, I62V, L63CS, A71V, I93L |
| >2233-30805| codons 4-99 TLWQRPIVTIKIEGQLKEALLDTGADDTVLEEMNLPGRWKPKIIVGIGGFIKVRQYDQVS IEICGHKVIGTVLVGPTPANVIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, M184V, L210W, T215Y | E44D, K102Q, V118VI, D123E, K166Q, D177E, I178L, G196GE, I202V, R211K, V245T |
| >2233-30805| codons 38-247 CTELEKDGKISKIGPENPYNTPVFAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKQKKSVTVLDVGDAYFSIPLDKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTQILEPFRKQNPELVIYQYVDDLYVGSDLEIEQHRTKVEELRQHLWKWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPITLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |