Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2102 | 2102-30701 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82A | L10F, L24I, L33F, K43T | I13V, E35D, M36I, N37D, K55KR, R57K, Q61QH, I62V, L63PQ, A71V, I93L |
| >2102-30701| codons 4-99 TLWQRPFVTVKIGGQLKEALIDTGADDTVFEDIDLPGRWTPKIIGGIGGFVRVKQYDHVQ IEICGHKVIGTVLVGPTPANIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74I, L210W, T215Y | K219R | V106A | F227L | K43KN, E44D, V111I, V118I, K122E, D177E, I178M, T200S, E203K, Q207E, H208Y, R211K |
| >2102-30701| codons 38-247 CTELENDGKISKIGPENPYNTPVFAIKKKNSTKWRKIVDFRELNKRTQDFWEVQLGIPHP AGLKKKKSATVLDIGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPEMVIYQYMDDLYVGSDLEIGQHRSKIKELREYLWKWGFYTP DRKHQKEPPLLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |