Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1416 | 1416-30610 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T215F | K101E, Y181C, G190S | T39A, D121Y, K122E, I178M, T200A, Q207G, R211K, L228R, V245T |
| >1416-30610| codons 38-247 CAELEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLEKKKSVTVLDVGDAYFSVPLYEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDMVICQYMDDLYVSSDLEIGQHRAKIEELRGHLLKWGFFTP DKKHQKEPPFRWMGYELHPDKWTVQPITLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82T, L90M | G73S | L10I, I13IMV, Q18H, K20R, M36I, I62V, L63P, I66IV, H69R, A71V, I93L, C95F, T96S |
| >1416-30610| codons 4-99 TLWQRPIVTVKIGGHLREALLDTGADDTVLEEINLPGRWKPKIIGGIGGFVKVRQYDQVP IEVCGRKVISTVLVGPTPTNIIGRNLMTQLGFSLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |