Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1414 | 1414-30822 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, K70R, V75M, M184V, T215F | K219Q | K103S, G190A | T39A, K43E, E44EA, V60I, V118I, K122E, D123N, I135T, S162D, V179VI, G196E, E203A, F214L, L228H |
| >1414-30822| codons 38-247 CAELEEAGKISKIGPENPYNTPIFAIKKKNSDRWRKLMDFRELNKRTQDFWEVQLGIPHP AGLKKSKSVTVLDVGDAYFSIPLDENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQDSMTKILEPFRKQNPDIIIYQYVDDLYVASDLEIEQHRTKIAELRQHLLRWGLFTP DQKHQKEPPFHWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, I54V, V82A | L33F | L10V, T12N, M36L, L38W, I62IV, L63P, A71V, I72IM, T74S, T91A, I93L |
| >1414-30822| codons 4-99 TLWQRPVVNIKIGGQLKEALLDTGADDTVFEELNWPGRWKPKMIVGIGGFVKVRQYDQVP IEICGHKVMGSVLVGPTPANIIGRNLLAQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |