<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1414 1414-30822 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, K70R, M184V, T215F V75M, K219Q K103S, G190A   T39A, K43E, E44EA, V60I, V118I, K122E, D123N, I135T, S162D, V179VI, G196E, E203A, F214L, L228H  
>1414-30822| codons 38-247
CAELEEAGKISKIGPENPYNTPIFAIKKKNSDRWRKLMDFRELNKRTQDFWEVQLGIPHP
AGLKKSKSVTVLDVGDAYFSIPLDENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQDSMTKILEPFRKQNPDIIIYQYVDDLYVASDLEIEQHRTKIAELRQHLLRWGLFTP
DQKHQKEPPFHWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
G48V, I54V, V82A L33F L10V, T12N, M36L, L38W, I62IV, L63P, A71V, I72IM, T74S, T91A, I93L  
>1414-30822| codons 4-99
TLWQRPVVNIKIGGQLKEALLDTGADDTVFEELNWPGRWKPKMIVGIGGFVKVRQYDQVP
IEICGHKVMGSVLVGPTPANIIGRNLLAQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006