Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1122 | 1122-30312 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54IATV, V82VA, I84IV | L24I, L33LF | L10I, R41RK, I62V, L63P, A71V, I72LV, N83NS, I85IMV, I93L |
| >1122-30312| codons 4-99 TLWQRPIVTIKIGGQLKEALIDTGADDTVFEEMNLPGKWKPKIIGGIGGFVKVRQYDQVP IEICGHKVVGTVLVGPTPASVVGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, T69DN, K70R | T215P, K219R | L100LI, K103N | V90VI, K102R, V118I, K122E, D123DN, I135IT, E203EK, R206RK, H208HY, R211K, F214L, L228HQ |
| >1122-30312| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKNSNRWRKLVDFRELNKRTQDFWEIQLGIPHP AGIKRNKSVTVLDVGDAYFSIPLDENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIKELKQYLLKWGLPTP DRKHQKEPPFQWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |