Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1106 | 1106-30617 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I84V, L90M | F53L, G73GS | L10I, E35D, M36MI, N37E, L63P, A71V |
| >1106-30617| codons 4-99 TLWQRPIVTIKIGGQLKEALLDTGADDTVLEDIELPGRWKPKIIGGIGGLIKVRQYDQIP IEICGHKVISTVLVGPTPVNVIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215Y | K219KNRS | K103N, Y181C | T39E, E44D, D123E, I135V, Q174R, E203K, R211K, K223E, L228H, K238KI | P226PT |
| >1106-30617| codons 38-247 CEELEKDGKISKIGPENPYNTPVFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKRNPDIVICQYMDDLYVGSDLEIGQHRTKIKELRQHLWKWGFYTP DSKHQEEPTFHWMGYELHPDIWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |