<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1383 1383-30507 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74V, M184V, L210W, T215Y K70S, K219Q M230L V179D T39A, E40F, K43E, K103R, K104KR, V111I, D123E, S162SA, I167V, G196E, Q207E, H208HY, R211K, V245M  
>1383-30507| codons 38-247
CAFLEEEGKISKIGPENPYNTPVFAIKKKNSTSWRKVVDFRELNKRTQDFWEVQLGIPHP
AGLKKRRSVTVLDIGDAYFSVPLDKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQASMTKVLEPFRKQNPDIDIYQYVDDLYVGSDLEIEQHRTKIEELREYLWKWGFYTP
DQKHQKEPPFLWLGYELHPDKWTVQPIMLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, I84V, L90M L33F L10I, G16A, I62V, L63P, I64L, A71T, V77I, Q92K, I93L  
>1383-30507| codons 4-99
TLWQRPIVTIKIAGQLKEALLDTGADDTVFEEMNLPGRWKPKLIGGIGGFVKVRQYDQVP
LEICGHKTIGTVLIGPTPVNVIGRNLMTKLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006