Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2004 | 2004-30623 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, I47V, I54L, I84V, L90M | L33F, M46V, G73T | L10V, I15V, L19I, K20R, E34A, E35D, M36I, P39S, L63P, I66IV |
| >2004-30623| codons 4-99 TLWQRPVVTIKVGGQIREALLDTGADDTIFADINLSGRWKPKVVGGIGGFLKVRQYDQIP IEVCGHKAITTVLVGPTPVNVIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L74I, V75T, M184V, T215F | K219Q | A98G | T69TN, V118I, K122E, D123G, I135IT, K173E, E203D, H208Y, F214L, K223E, L228H |
| >2004-30623| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKKKNSNRWRKITDFRELNKRTQDFWEVQLGIPHP GGLKKKKSVTVLDVGDAYFSIPLDEGFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFREQNPDIVIYQYVDDLYVGSDLEIGQHRTKIDELRQYLLRWGLFTP DQKHQEEPPFHWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |