Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1879 | 1879-30605 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, I54A, V82A | L24I, L33F, K43T | L10I, M36L, N37D, D60E, I62V, L63P, I64V, A71T, T91A |
| >1879-30605| codons 4-99 TLWQRPIVTIKIGGQLKEALIDTGADDTVFEELDLPGRWTPKMIVGIGGFAKVRQYEQVP VEICGHKTIGTVLVGPTPANIIGRNLLAQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70RS, V75M, M184V, L210W, T215Y | K219E | A98AG | T39A, E44D, S68G, V118VI, D121DH, K122E, I135L, R211K, L228H, P243T, V245E |
| >1879-30605| codons 38-247 CAELEKDGKISKIGPENPYNTPVFAIKKKNGTSWRKLMDFRELNKRTQDFWEVQLGIPHP GGLKKKKSVTVLDVGDAYFSIPLHEDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIGQHRTKIEELRQHLWKWGFYTP DEKHQKEPPFHWMGYELHPDKWTVQTIELP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |