Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1692 | 1692-30423 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46ML, G48GA, I54V, V82A, L90M | L33F, K43T, T74TP | L10I, I13V, K20R, E35D, M36I, N37S, R41K, K55KR, I62V, L63P, A71T, I93L |
| >1692-30423| codons 4-99 TLWQRPIVTVKIGGQLREALLDTGADDTVFEDISLPGKWTPKLIAGIGGFVRVRQYDQVP IEICGHKTIGPVLVGPTPANIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, M184V, L210W, T215Y | G190A | K101H | V118VI, K122KE, D123DN, V179VI, R211RK, F214FL | K43KHNQ |
| >1692-30423| codons 38-247 CTELEQEGKISKIGPENPYNTPVFAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHP AGLHKKKSVTVLDVGDAYFSIPLDENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDIIIYQYVDDLYVASDLEIGQHRTKIEELRQHLWKWGLYTP DKKHQKEPPFLWMGYELHPDKWTVQPIVLP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |