Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1369 | 1369-30717 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, V75AT | K219E | K103N, Y181C | V60I, K64KR, V106VI, K122E, I135T, I178M, E203K, Q207E |
| >1369-30717| codons 38-247 CTEMEKEGKISKIGPENPYNTPIFAIRKKNSTRWRKLTDFRELNKRTQDFWEVQLGIPHP AGLKKNKSITVLDVGDAYFSVPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDMVICQYMDDLYVGSDLEIGQHRTKIKELREHLLRWGFTTP DEKHQKEPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, I84V | L10I, T12S, I13V, I15IV, Q18H, K20T, M36I, N37D, I62V, L63P, A71V | P79PHSY |
| >1369-30717| codons 4-99 TLWQRPIVSVKVGGHLTEALLDTGADDTVLEEIDLPGRWKPKMIGGIGGFVKVRQYDQVP IEICGHKVIGTVLVGYTPVNVIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |