Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1367 | 1367-30618 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, I84V, L90M | V11I, L33F, K43T, L89V | L10I, T12P, I13V, K14R, K20M, E35D, M36I, I62V, L63P, A71V, T91S, Q92K |
| >1367-30618| codons 4-99 TLWQRPIIPVRIGGQLMEALLDTGADDTVFEDINLPGRWTPKMIGGIGGFVKVRQYDQVP IEICGHKVIGTVLVGPTPANVIGRNVMSKIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, V75M, M184V, L210W, T215Y | K101E, Y181C, G190A | V108I | K43E, E44D, K49R, T69TN, V118I, K122E, I135R, S162N, Q174QR, G196E, R211K, H221Y, L228R, I244V, V245E |
| >1367-30618| codons 38-247 CTELEEDGKISRIGPENPYNTPVFAIKKKDSNKWRKLMDFRELNKRTQDFWEVQLGIPHP AGLEKKKSVTILDVGDAYFSIPLDEDFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSP AIFQNSMTKILEPFRKRNPDIVICQYVDDLYVASDLEIEQHRTKIEELRQHLWKWGFYTP DKKYQKEPPFRWMGYELHPDKWTVQPVELP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |