<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1361 1361-30616 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, M184V, L210W, T215Y   K103N, Y188L   T39A, K43E, E44D, K49R, E53D, A98S, V118I, K122E, D123DN, S162D, D177G, G196E, T200A, E203K, Q207E, H208HY, R211K, V245M K223KPQT
>1361-30616| codons 38-247
CAELEEDGKISRIGPDNPYNTPVFAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHP
SGLKKNKSVTVLDVGDAYFSIPLDENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQDSMTKILEPFRKQNPGIVIYQYVDDLLVGSDLEIEQHRAKIKELREYLWKWGFYTP
DKKHQTEPPFLWMGYELHPDKWTVQPIMLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A, I84V, L90M V11I, L33F, G73T L10I, I13V, L19I, E34Q, I62V, L63P, C67L, A71V, I72M, V77I  
>1361-30616| codons 4-99
TLWQRPIITVKIGGQIKEALLDTGADDTVFQEMNLPGRWKPKMIGGIGGFVKVRQYDQVP
IEILGHKVMTTVLIGPTPANVIGRNLMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006