<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1357 1357-30625 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70G, L74I, V75T, L210W, T215F K219W Y181C, G190A V108I E79ED, K82KR, K122P, I167V, I178M, T200A, E203D, E204K, Q207E, R211K, L228H  
>1357-30625| codons 38-247
CTELEKEGKISKIGPENPYNTPVFAIKKKNSTGWRKITDFRDLNRRTQDFWEVQLGIPHP
AGLKKKKSVTILDVGDAYFSVPLDPDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKVLEPFRKQNPDMVICQYMDDLYVASDLEIGQHRAKIDKLREHLWKWGFFTP
DWKHQKEPPFHWMGYELHPDKWTVQPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A, I84V, L90M L33F L10I, N37D, K55R, I62V, L63P, A71V, I72IT F53FS
>1357-30625| codons 4-99
TLWQRPIVTIKIGGQLKEALLDTGADDTVFEEMDLPGRWKPKLIGGIGGSVRVRQYDQVP
IEICGHKVTGTVLVGPTPANVIGRNLMTQIGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006