Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2169 | 2169-30813 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I84V | L10F | I13V, K20KR, L63P, I64V, K70R |
| >2169-30813| codons 4-99 TLWQRPFVTVKIGGQLREALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQIP VEICGHRAIGTVLVGPTPVNVIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, L210W, T215Y | K219E | A98AG, V108VI | K122E, K126E, S134R, I135T, I178L, T200A, H208HY, R211RK, D218DE, V245E | K49T, K82Q, N137T |
| >2169-30813| codons 38-247 CTEMEKEGKISTIGPENPYNTPVFAIKKKNSTRWRKLVDFRELNQRTQDFWEVQLGIPHP GGLKKKKSVTILDVGDAYFSVPLDEDFREYTAFTIPRTNTETPGIRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPDLVIYQYMDDLYVGSDLEIGQHRAKIEELRQYLWKWGFYTP EEKHQKEPPFLWMGYELHPDKWTVQPIELP |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |