Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2167 | 2167-30702 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T69S_XG, L74I, M184MV, T215Y | D67G | K103N | V108I, P225H | R83K, K102Q, D123E, I135T, S162Y, I178ILM, T200A |
| >2167-30702| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFAIKKKGSSKWRKIVDFRELNKKTQDFWEVQLGIPHP AGLKQNKSVTILDVGDAYFSVPLDKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP AIFQYSMTKILEPFRKQNPDMVIYQYVDDLYVGSDLEIGQHRAKIEELRQHLLRWGFYTP DKKHQKEHPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N, I50L | L10LF, V11VI, L33I, N88D | I13V, E35D, M36I, K45KI, R57K, L63P, A71T |
| >2167-30702| codons 4-99 TLWQRPFITVKIGGQLKEALLDTGADNTVIEDINLPGRWKPIMIGGLGGFIKVKQYDQIP IEICGHKTIGTVLVGPTPVNIIGRDLLTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |