Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-2182 | 2182-30627 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, M184V, T215Y | K103N, Y181C | K122E, I135T, I142T, E169D, V179VI, T200A, I202V, V245M |
| >2182-30627| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHP AGLKKNKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSTNNETPGTRYQYNVLPQGWKGSP AIFQSSMTKILDPFRKQNPDIIICQYVDDLYVGSDLEIGQHRAKVEELRQHLLRWGFYTP DKKHQKEPPFLWMGYELHPDKWTVQPIMLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I47V, I54V, V82A, L90M | V11I, F53FL, G73S | L10I, I15V, Q18H, K20I, M36I, N37D, K55R, L63P, A71V, I72IV, I85V |
| >2182-30627| codons 4-99 TLWQRPIITIKVGGHLIEALLDTGADDTVLEEIDLPGRWKPKIVGGIGGLVRVRQYDQIP IEICGHKVVSTVLVGPTPANIVGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |