<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
12-1967 1967-30621 U.S. 2003 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI|NRTI|NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74I, M184V, T215Y V75T, K219Q K103S, Y181C, G190A   K122E, D123DGNS, I142V, D177E, I178M, T200A, Q207K, R211AT, F214L, D218E, L228R, V245VM  
>1967-30621| codons 38-247
CTELEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKITDFRELNKRTQDFWEVQLGIPHP
AGLKKSKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPEMVICQYVDDLYVASDLEIGQHRAKIEELRKHLLTWGLYTP
EQKHQKEPPFRWMGYELHPDKWTVQPIMLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I47V, I54M, L76V, I84V, L90M L10F, V11I, G73S, L89V I15V, K20I, E34Q, M36I, D60E, I62V, L63P, A71I, I93L  
>1967-30621| codons 4-99
TLWQRPFITIKVGGQLIEALLDTGADDTVLQEINLPGRWKPKIVGGIGGFMKVRQYEQVP
IEICGHKIISTVVVGPTPVNVIGRNVMTQLGCTLNF

References
Author Title Citation
Baxter, JD Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. J Virol, 2006