Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 12-1967 | 1967-30621 | U.S. | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | PI|NRTI|NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74I, V75T, M184V, T215Y | K219Q | K103S, Y181C, G190A | K122E, D123DGNS, I142V, D177E, I178M, T200A, Q207K, R211AT, F214L, D218E, L228R, V245VM |
| >1967-30621| codons 38-247 CTELEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKITDFRELNKRTQDFWEVQLGIPHP AGLKKSKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSP AIFQSSMTKILEPFRKQNPEMVICQYVDDLYVASDLEIGQHRAKIEELRKHLLTWGLYTP EQKHQKEPPFRWMGYELHPDKWTVQPIMLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I47V, I54M, L76V, I84V, L90M | L10F, V11I, G73S, L89V | I15V, K20I, E34Q, M36I, D60E, I62V, L63P, A71I, I93L |
| >1967-30621| codons 4-99 TLWQRPFITIKVGGQLIEALLDTGADDTVLQEINLPGRWKPKIVGGIGGFMKVRQYEQVP IEICGHKIISTVVVGPTPVNVIGRNVMTQLGCTLNF |
References
| Author | Title | Citation |
| Baxter, JD | Genotypic changes in human immunodeficiency virus type 1 protease associated with reduced susceptibility and virologic response to the protease inhibitor tipranavir. | J Virol, 2006 |